Rough ER: The main difference between me and my brother the Sooth ER is that I am studded with ribosomes while he is not. The entirety of me is responsible for the synthesizing of lipids, the modification of many proteins. I am also the origin of intracellular transport vesicles that carry said proteins. Myself being the Rough ER, I am responsible the manufacturing of proteins that are destined for secretion or for incorporation into membranes.
Smooth ER: Now for my little brother. He is responsible for the biosynthesis of lipids and the detoxification of drugs that enter the body of a plant of animal.
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